Sputum Inflammatory Profile Before and After Specific Inhalation Challenge in Individuals with Suspected Occupational Asthma
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چکیده
منابع مشابه
Sputum Inflammatory Profile Before and After Specific Inhalation Challenge in Individuals with Suspected Occupational Asthma
BACKGROUND The aim of this study was to establish the sputum inflammatory profile and changes in levels of leukotriene B₄ (LTB₄) and a panel of Th1/Th2 cytokines in subjects with suspected occupational asthma (OA) following specific inhalation challenge (SIC) to high-molecular-weight (HMW) and low-molecular-weight (LMW) agents. MATERIAL AND METHODS Fifty-one consecutive subjects undergoing SI...
متن کاملManuscript cited in "Specific inhalation challenge in the diagnosis of occupational asthma: consensus statement".
This consensus statement provides practical recommendations for specific inhalation challenge (SIC) in the diagnosis of occupational asthma. They are derived from a systematic literature search, a census of active European centres, a Delphi conference and expert consensus. This article details each step of a SIC, including safety requirements, techniques for delivering agents, and methods for a...
متن کاملFailure of sputum eosinophilia after eotaxin inhalation in asthma.
BACKGROUND Eotaxin is a chemokine specific for eosinophils and may play an important role in eosinophil recruitment in asthma. The effects of eotaxin inhalation on sputum and blood eosinophils, exhaled nitric oxide (NO), and bronchial responsiveness were determined. METHODS Eotaxin was administered by nebulisation to asthma patients in three studies: (1) an open dose finding study with eotaxi...
متن کاملSpecific inhalation challenge tests for occupational asthma in Europe: a survey.
Taishi Harada, Yuji Yoshida, Yasuhiko Kitasato, Nobuko Tsuruta, Kentaro Wakamatsu, Takako Hirota, Makoto Tanaka, Naoki Tashiro, Hiroshi Ishii, Motokimi Shiraishi, Masaki Fujita, Nobuhiko Nagata and Kentaro Watanabe Dept of Respiratory Medicine, Fukuoka University School of Medicine, Fukuoka, Japan. Dept of Respiratory Medicine, Kurume Dai-ichi Hospital, Kurume, Japan. Dept of Respiratory Medici...
متن کاملSpecific inhalation challenge in the diagnosis of occupational asthma: consensus statement
This consensus statement provides practical recommendations for specific inhalation challenge (SIC) in the diagnosis of occupational asthma. They are derived from a systematic literature search, a census of active European centres, a Delphi conference and expert consensus. This article details each step of a SIC, including safety requirements, techniques for delivering agents, and methods for a...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0078304